The Cleveland Clinic Lou Ruvo Center for Brain Health designed by Frank Gehry is unique with an undulating roof that reaches up seven floor in Las Vegas, Jan 1, 2010. Funded by Las Vegas liquor distributor Larry Ruvo, it has changed the Las Vegas skyline. It has 550 interlocking stainless steel pieces, no two alike, at all sorts of angles and the design is said to elevate awareness of Alzheimer's disease. The building serves as the headquarters for Keep Memory Alive, the Las Vegas Alzheimer's Association and the Las Vegas Parkinson's Disease Association. [Photo/CFP]